Jeffrey Epstein, the disgraced millionaire who was facing federal sex trafficking charges, died by suicide Friday night in his Lower Manhattan jail cell, three law enforcement officials told ABC News.

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The exact timing and circumstances were not immediately clear.
Epstein, 66, was set to stand trial next year for allegedly sexually abusing dozens of minor girls in New York and Florida.
(MORE: The rise and fall of Jeffrey Epstein: A timeline of the financier's legal troubles)
PHOTO: An undated handout photo made available by New York State Division of Criminal Justice showing Jeffrey Epstein, issued 25 July 2019.New York State Division of Criminal Justice/EPA-EFE/REX
An undated handout photo made available by New York State Division of Criminal Justice showing Jeffrey Epstein, issued 25 July 2019.
His death came less than three weeks after he was found unresponsive in his cell at Metropolitan Correctional Center in Lower Manhattan, with marks on his neck that appeared to be self-inflicted, sources told ABC News.
He had been on suicide watch since the July 23 incident.
(MORE: Former lead prosecutor tried to ‘prosecute Jeffrey Epstein to the fullest extent of the law’: Lawyer)
Epstein was arrested on July 6 for alleged sex trafficking of minor girls at his Upper East Side mansion and his home in Palm Beach, Florida. Some of the charges date back to the early 2000s.
Epstein, 66, pleaded not guilty to the charges. He faced up to 45 years in prison if convicted.
(MORE: Millionaire and convicted sex offender Jeffrey Epstein put on suicide watch after being found injured in jail: Source)
PHOTO: Financier Jeffrey Epstein looks on near Judge Richard Berman during a status hearing in his sex trafficking case, in this court sketch in New York, July 31, 2019Jane Rosenburg/Reuters
Financier Jeffrey Epstein looks on near Judge Richard Berman during a status hearing in his sex trafficking case, in this court sketch in New York, July 31, 2019more +
His alleged crimes were thrown back into the spotlight amid renewed scrutiny of the plea deal Epstein reached with the U.S. Attorney’s Office in Miami in 2007, led by then-U.S. Attorney Alexander Acosta. A non-prosecution agreement allowed Epstein, a hedge-fund manager, to plead guilty to two state charges and avoid federal charges for an allegedly broad pattern of similar sexual misconduct. He would serve just 13 months of an 18-month sentence in county jail in Florida.
(MORE: Millionaire Jeffrey Epstein's sex-trafficking trial set for next year; a million pages of discovery expected)
The victims in that case were not made aware of the negotiations for nearly a year after the agreement was signed, according to their attorney.
The deal is currently under review by the Justice Department’s Office of Professional Responsibility. Acosta was serving as President Trump's Labor Secretary amid the controversy over his role in the deal. He later resigned from that position.
This is a developing story. Please check back for updates